Interesting Factors Influencing Wound Healing Process in a Nutshell!

 

Interesting Factors Influencing Wound Healing Process in a Nutshell!
Interesting Factors Influencing Wound Healing Process in a Nutshell: Photo by RDNE Stock project:


Everyone of you may have experience cuts, bruises, scratches or burns etc. in day to day life. Especially, if you have children, they tend to get more and more wounds while they are playing, due to falls etc. On the other hand, if left untreated, these wounds can give painful complications too. So, knowing the factors influencing wound healing may help you get back to normal driving you another step towards a healthy and happy life!

 

Two Main Aspects of the Process of Wound Healing

 

There are two main aspects of wound healing process.

1.     Contraction of the wound

In any wound, the margins approximate and there will be a mechanical reduction in the size of the wound. However, depending on the size of the wound the degree of this contraction may close the defect as in small wounds and it may simply reduce the size only as in bigger wounds.

2.     Replacement of the lost tissues

The cells in the margins of the wound will proliferate and migrate. They will try to fill in the gap or the defect wherein replacing the lost tissues.

There are two ways of achieving this. When the adjacent specialized cells have the capacity to proliferate, they will proliferate and fill in the gap eventually. This is called Regeneration. This is evident in organs like liver.

The second way is to heal from repair by granulation tissue. This happens when the adjacent specialized cells do not have the capacity to proliferate. So, initially the wound surface will form a granulation tissue and it will become a scar tissue eventually. This is evident in almost all the skin wounds.

The red colored surface on a wound is the external appearance of granulation tissue that you see in skin wounds. As the wound ages, this will become white and this is the scar tissue that persists for life on the skin of affected area. If the wound is very small, these scars will be erased with time whereas in bigger wounds, these scars would persist for many years.

 

Factors Influencing Wound Healing

 

There are many factors influencing wound healing. Firstly, Local factors are the factors related to the wound area and the surroundings. Secondly, General factors are the factors that affect all the systems of the body in general so that they will affect the healing process of your wound too.

 

Local Factors Influencing Wound Healing

 

The effect of Blood supply

 

A wound is an active area of the body where cells proliferate, migrate and differentiate etc. Thus, these cells need good nutrition, Oxygen and so forth. Therefore, the wounds in the tissues with a good blood supply tend to heal quickly. Conversely, the wounds in the areas with poor blood supply may take weeks to months to heal.

Anatomically, some areas of the body like the front of the lower leg have poor blood supply so the wounds in that area may take some time to heal. Likewise, some disease conditions like diabetes, hyperlipidemia, atherosclerosis, etc. make your blood vessels weak. Therefore, the blood supply in general may be affected and mostly, the wounds in the peripheries like hands, feet may take time to heal. Most importantly, smoking is another factor that weaken your blood vessels leading to poor wound healing.

 

Infection and Inflammation

 

If the wound is infected with bacteria, fungi, etc. the surrounding tissues will become inflamed. However, the tissue death due to the effect of bacteria will be a hindrance to the healing process. Similarly, chemical, disinfectants, foreign bodies like dirt also can make irritation of the wound leading to the inflammation that will cause poor wound healing.

Sometimes, you can damage the delicate wound surface by rough handling of wound dressing material. Needless to say, that you need to elicit extreme care while wound dressing to achieve faster wound healing.

Some scientific evidence shows that when the underlying tissues of the wounds can attach to other structures like bone. So that the contraction of the wound doesn’t occur properly. Obviously, this will delay healing.

 

The effect of Physical Factors like Movement, the Direction of the wound and its Location

 

Research show that when a person is mobile, this will affect in delayed wound healing when compared to a person kept in rest. Truly, when a wound is located on a joint or on a skin crease of a joint, the movement of that respective joint will negatively affect its healing process. The ultimate result would be the delayed wound healing.

Another important fact is that when a wound is parallel to the crease lines of the skin, they tend to heal quickly while the wounds which are perpendicular to the crease lines will take some time to heal.

 

Drying

 

When a wound is left open to the environment, it will become dry. This will be covered by a hard crust that will lead to a delayed healing. There should be some moisture for wounds to heal quickly. Applying a dressing with Vaseline will achieve this.

 

Effects of Radiation

 

Scientific evidence says that Ultra-violet rays can improve the wound healing process while X radiation can diminish wound healing by delaying the formation of granulation tissue. So, staying in some direct sunlight may not do any harm. Isn’t it?

 

 

General Factors Influencing Wound Healing

 

Age

 

Wound healing is faster in young population when compared to old age.

 

Effect of proper Nutrition

 

As discussed above, wound healing process is a dynamic process which needs energy. However, the formation of the granulation tissue needs proteins in your diet. That is because specific proteins act as constituents of new granulation tissue. Thus, if you encounter a protein deficiency in your diet, wound healing will take a long time.

Likewise, the deficiency of Iron in your diet can cause poor wound healing. Iron is important as a main constituent in Hemoglobin in your Red blood cells. Hemoglobin helps bind oxygen molecules and transport them to the tissues. So definitely, poor hemoglobin content will affect poor oxygenation of wound tissue causing poor wound healing. Most importantly, this is another reason why you should take a diet rich in Iron.

Similarly, if your diet is deficient in Vitamin C, that will cause poor wound healing. In the lack of Vitamin C, the granulation tissue is formed but it is abnormal so it will take a long time for your wounds to heal.

Moreover, research says that adding Zinc to your diet can increase the rate of wound healing specially, in burns. This is probably due to the fact that Zinc is an important constitute of many enzymes. But there is some contradictory evidence say that when you take Zinc sulphate as an oral supplement, there was no significant result. But moderate increase of Zinc content in your diet may not harm you when you are suffering from a wound!

 

Effect of Hormones

 

Some hormones like Glucocorticoids can slow down your wound healing if taken in higher amounts. This is because this hormone can impair wound contraction and the formation of the granulation tissue.

On the other hand, some hormones like Testosterone can promote wound healing.

 

Temperature

 

In general, cold weather is an inhibitory factor for wound healing while sunny weather can speed up wound healing. As discussed above, UV light of sunrays may be playing a role.

 

Supplements to Promote Wound Healing

 

With these factors affecting wound healing in your mind, you can easily work out how to speed up scab healing with the correct supplement. Likewise, there are a whole a lot of natural food choices can give you the same result too.

This is very important in occasions like when you face a surgery. Knowing how to speed up wound healing after surgery will definitely improve the quality of your life. So, supplements or food that promote wound healing after surgery should include Proteins, Iron, vitamin C and Zinc.

 

In conclusion,

 

To sum up, Wound contraction and replacement of lost tissue are the two main aspects of wound healing process. There are Local and General factors influencing wound healing in many ways. You can modify your lifestyle choices to optimize most of these factors to have improved wound healing for a speedy recovery!


Good luck

From Dr. Pasindu

Stay happy stay healthy


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